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Instructions
for use
MOTS-c Pen
Pharmacological properties
MOTS-c (mitochondrial derived peptide MDP-s, Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded by mitochondrial DNA. It participates in the regulation of energy metabolism, glucose and lipid metabolism, and cellular stress responses. The peptide activates AMPK (adenosine monophosphate-activated protein kinase), a key regulator of cellular energy balance. MOTS-c is a promising peptide in the context of metabolism control, aging, endurance, longevity, and processes leading to diseases such as osteoporosis.
Composition
Pen-vial (2.5 ml) contains:
MOTS-c, 25 mg
Water for injection
Indications for use
01
Obesity and overweight: MOTS-c reduces body weight, promotes fatty acid oxidation, and improves insulin sensitivity: MOTS-c increases glucose uptake by muscles, activates AMPK, and raises GLUT4 transporter levels.
02
Anti-aging effects: Increased MOTS-c in the blood improves physical activity, reduces inflammation, and enhances endurance in adulthood.
Contraindications
01
Hypersensitivity to MOTS-c or excipients
02
Pregnancy and lactation (due to insufficient clinical data)
03
Children under 18 (without clinical recommendations)
Method of administration and dosage
Method of administration: subcutaneous.
Before the first injection, it is essential to dial 20 units on the pen-injector and push the plunger to the "0" mark until the first drop of the medication appears. If no drop appears, repeat the procedure.
Pen-vial
25 mg / 2.5 ml
Single dose
25u=2.5 mg
Frequency
once every 6 days
Administration time
morning/day
Injections from 1st vial
10 injections (2.5mg)
Vials per course
1 pen-vial
Rotate injection sites:
abdomen, shoulder, thigh, buttock.
Rate of administration:
30–60 sec/0.1 ml
One pen lasts for approximately 10 weeks
Possible side effects
Local:
erythema, itching, induration.
Systemic:
headache, dizziness, dyspepsia.
If severe reactions occur, discontinue therapy and provide symptomatic treatment.
Special instructions
01
Gradually titrate the dose.
02
In case of adverse reactions, adjust the dose or temporarily discontinue use.
03
Once opened, store the vial at 2–8°C and use within one month.
04
Do not mix with other medicinal products in the same syringe.
Shelf life
The shelf life of MOTS-c is when stored at 2–8°C and protected from light. Do not use after the expiration date indicated on the package.
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